Skip Navigation

About the Malaria Team

mosquito feeding

The Malaria Team is instrumental in the design and implementation of the MaHPIC’s Anopheles mosquito and non-human primate infection protocols, to achieve as required the development of infectious sporozoites in mosquitoes, infection of the animals, and the timely collection and processing of biological samples for in-house experimentation and analysis as well as by the various MaHPIC Teams.  The Malaria Team’s responsibilities include carrying out and monitoring all clinical procedures associated with the experimental malaria infections. In the course of such infections with different species or combination of Plasmodium species, the Malaria Team gathers clinical, clinical biochemistry, hematological and parasitological information that becomes organized in the form of data tables. The Malaria Team is also responsible for relating the non-human primate experiments and data to human samples contributed for analysis from several malaria endemic parts of the world.  All non-human primate studies involving the Malaria Team are carried out according to Institutional Animal Care and Use Committee (IACUC) approved procedures and protocols.  Samples being analyzed from humans have also been approved or declared exempt by the Institutional Review Board (IRB), as required.    

Aikawa, M., Brown, A., Smith, C.D., Tegoshi, T., Howard, R.J., Hasler, T.H., Ito, Y., Perry, G., Collins, W.E., and Webster, K. (1992). "A primate model for human cerebral malaria: Plasmodium coatneyi-infected rhesus monkeys." American Journal of Tropical Medicine & Hygiene, 46(4): 391-397. View in PubMed

Collins, W.E., Warren, M., Sullivan, J.S., and Galland, G.G. (2001). "Plasmodium coatneyi: observations on periodicity, mosquito infection, and transmission to Macaca mulatta monkeys." American Journal of Tropical Medicine & Hygiene, 64(3-4): 101-110. View in PubMed

Galinski, M.R., and Barnwell, J.W. (2012). "Nonhuman Primate Models for Human Malaria Research." Nonhuman Primates in Biomedical Research. K.M. Christian R. Abee, Suzette Tardif and Timothy Morris, editor. London: Academic Press. 299-323.

Moreno, A., Garcia, A., Cabrera-Mora, M., Strobert, E., and Galinski, M.R. (2007). "Disseminated intravascular coagulation complicated by peripheral gangrene in a rhesus macaque (Macaca mulatta) experimentally infected with Plasmodium coatneyi." American Journal of Tropical Medicine & Hygiene, 76(4): 648-654. View in PubMed