About the Lipidomics Team
The Lipidomics Team uses liquid chromatography/tandem mass spectrometry (LC-MS/MS) to permitd etailed targeted analyses of dynamical changes in lipid profiles resulting from malarial infectionsin non-human primates. Lipidomic analyses are performed on whole blood, blood cell membranes, and bone marrow, sampled from non-human primates during the course of malaria infections. The lipid panel includes ceramides, cholesterol esters, diacyl glycerides, glucosylceramides, ganglioside GM3, lactosylceramides, phosphatidic acids, phosphaditylcholines, phosphatidylethanolamines, phosphatidylinositols, phosphatidylserines, sphingomyelins, and sulfatides.
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Nagao, E., K. B. Seydel, et al. (2002). "Detergent-resistant erythrocyte membrane rafts are modified by a Plasmodium falciparum infection." Experimental Parasitology, 102(1): 57-59. View in PubMed
Riethmüller, J., A. Riehle, et al. (2006). "Membrane rafts in host-pathogen interactions." Biochimica et Biophysica Acta (BBA), 1758(12): 2139-2147. View in PubMed
Van der Meer-Janssen, Y. P. M., J. van Galen, et al. (2010). "Lipids in host-pathogen interactions: Pathogens exploit the complexity of the host cell lipidome." Progress in Lipid Research, 49(1): 1-26. View in PubMed
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