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Tracey Lamb, Ph.D.


Position

Immune Profiling Team, 
University of Utah


Role in MaHPIC

Immune Profiling Team,
University of Utah


Contact

E-mail: tracey.j.lamb@emory.edu


Personal Statement

I have over 10 years of experience using mouse models of malaria and my lab is now undertaking parallel research into human malaria in collaboration with researchers in Nigeria and the Cameroon. I have a broad background in the field of immunoparasitology, and have generated a body of work spanning several different mouse models of parasitic infection. The influence of co-infecting pathogens on the immunobiology of malaria infection is one of my long-standing research interests. As a postdoctoral Career Development Fellow at the National Institute of Medical Research in London, UK, I specialized in malaria immunology using the Plasmodium chabaudi mouse model to examine how the inflammatory immune response is regulated. I am now continuing with this line of research, focusing on the CD4+ T helper cells that orchestrate the immune response in malaria infection. Currently the aim of my research is to determine how the inflammatory immune response is activated and regulated during malaria infection. Specifically we investigate how CD4+T cells become activated and traffic to the organs of the body where malaria parasites sequester. The long term goal of my research is to generate knowledge on the basic immunobology of malaria infections that can be fed into the development of rationally designed therapeutic strategies for malaria. The systems biology approaches used by MAHPIC will elucidate the key features of protective and pathogenic immune responses that arise in malaria infection.